Ethical Analysis of Communicating the Risk of Iatrogenic Creutzfeldt-Jakob Disease

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Ethical analysis of communicating the risk of iatrogenic Creutzfeldt-Jakob disease.

To the Editor—The University of Michigan Health System Adult Ethics Committee recently convened to discuss whether 57 patients should be informed of possible exposure to classic Creutzfeldt-Jakob disease (CJD) after a neurosurgical patient was suspected of contracting CJD. Current routine sterilization procedures are believed to be ineffective against prions; thus, subsequent neurosurgical pati...

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Iatrogenic transmission of Creutzfeldt-Jakob disease.

Creutzfeldt-Jakob disease is a rare progressive neurological disorder which is eventually fatal. Attention has recently been focused upon the iatrogenic transmission of this disease by four published reports of patients developing Creutzfeldt-Jakob disease associated with the administration of human growth hormone preparations originally prepared from human cadaver pituitaries. Characterized cl...

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Iatrogenic Creutzfeldt-Jakob Disease, Final Assessment

The era of iatrogenic Creutzfeldt-Jakob disease (CJD) has nearly closed; only occasional cases with exceptionally long incubation periods are still appearing. The principal sources of these outbreaks are contaminated growth hormone (226 cases) and dura mater grafts (228 cases) derived from human cadavers with undiagnosed CJD infections; a small number of additional cases are caused by neurosurg...

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Iatrogenic Creutzfeldt-Jakob disease: the waning of an era.

The outbreaks of iatrogenic Creutzfeldt-Jakob disease (CJD) from cadaveric human growth hormone and dura mater are winding down and, like the only other environmentally acquired form of CJD (variant CJD due to infection with the agent of bovine spongiform encephalopathy), iatrogenic disease seems to have reached its high water mark during the 1990s. The total number of cases has reached 405, an...

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ژورنال

عنوان ژورنال: Infection Control & Hospital Epidemiology

سال: 2009

ISSN: 0899-823X,1559-6834

DOI: 10.1086/599004